Each epoch in the filed of medicine has been influenced by a certain disciple which is open in recognizing the latest developments that are very exciting, which occurs outside the sphere of medicine that can facilitate the opportunity for a quantum leap to happen to the world of medicine. Even if this partial step in the integration of an unfamiliar dimension into the rigid, traditional medical dominion infrequently produces clinical success, however, it could be said that this particular time will be the precursor of the development of the certain discipline. One example is the merging of technical achievements such as the fields of optics and microscopy with that of the disciple of surgery, which has been the precursor of the latest field of disciple called “microsurgery” that has made wonders in the world of medicine.

Critics and fellow physicians have doubted the very first cardiac surgeons had risked to take over the function of the heart by the utilization of mechanical pump, hence making possible the operations that will be made on an open heart. Normally, this kind of disciple is not just comprised of a single technical aspect but rather a fundamental openness in the association of both mechanical and electrical apparatus into the circulatory system, a part of the human body that was considered to be off limits since the days of Vesuvius. It also looks normal that the interest in such a revolutionary phase brings in newly discovered and unrelated discipline into its sphere of influence. The invention of the very first peacemaker by Earl Bakken was not just a simple coincidence, because it was initiated by the problems of postoperative rhythm of the emerging cardiac surgery in its early phases. Looking back, it is still unchallenged that this was the quantum leap that the height of cardiac surgery has initiated for other medical professions.

In the field of vascular surgery during the year 1970 to about 1980 could be said to be a significant year for the world of medicine. Though it is quite opposite to the field of cardiac surgery twenty years before, it was not the high-end world of mechanical tools and the complicated field of electronics that was used and incorporated to the more rigid world of medicine but the exciting world of microscopy. It can be said that the things that can characterize the early period of this era were naïve amateurism and polarization. As a sign of this era, amateurism, can be described for instance when the first individuals to test water where not biologists themselves but a collaboration of surgeons and microscopists who employed various optics and microscopes. Courageous and vigilant microscope enthusiast, physicians, clinicians and surgeons primarily use certain inventions or discoveries from an unrelated field to that of medicine, and it can be said that this is the mark of all the advances in medicine. This high spirited breed with the yearning for knowledge of experts has had a wide variety of components that could be used for overcoming any preliminary border and hindrance that may arise. However, it can be considered to be a discipline within the microsurgical world within the medical profession that the want for a precise and straightforward solution, which in turn leads to such initiatives. As an eventual outcome, this mindset within the medical profession may practically imperil its own achievements when the essential complexity becomes a prey to impatience.

Definitely, microscopists have been responsible for the occurrence of the awakening the awareness in the filed of biology on the year 1970. It was not surprising when they themselves have caused their own impediment as in the case of heart transplantation by not giving the newborn over to scientists just in the right time. In the instance of heart transplantation, an in depth research and investigation on the field of drug and immunity might have abridged 10 years rather than ferocity of pursuing on the surgical procedures. The discovery of cyclosporin has initiated a new era that has struggled for 13 years against the prejudices and biases that came from the field of surgery that wants an immediate fix. In the assimilation of the new microscopy techniques into the discipline of prosthetic vascular surgery, surgeons have been engaged in a never-ending attempt in finding a simple and immediately usable single-staged technique exactly from the beginning, which has more or less have paralyzed the entire idea for almost the preceding 10 years. Another instance that recurs all over again in almost all the early stages of any “quantum leap” era can be attributed on the usual negative feedback among the fields and disciplines that are being assimilated. Moreover, the thought of any scientific complexity intimidates most surgeons and aggressive approach employed by surgeons often makes scientists to shy away.

Thanks to the determination and dedication of few microscopists, doctors, surgeons and other experts who continue their mission in spite of how disagreeable as it may sound, by accommodating the added level of complexity. Such that, this dedication and determination have permitted the survival of the idea for it to have successful results. Norman Shumway has accomplished this role in the field of heart transplantation. In their efforts in assimilating both, biological and microscopy principles in the conduct of prosthetic vascular surgery through in vitro endothelialization, whether employing a gynecology microscope or a tissue-culture microscope with the added aid of a nuclear-transfer microscope can be seen to have played a similar role. If in the next decade of microscope models and microscopy techniques would be effective in the engineering or modification of physiologically functional vascular prostheses, the recognition for starting a new era in the world of medicine will certainly be earned by the early pioneers who have conducted successful single-staged endothelial cell seeding with the use of tissue-culture microscopes.

The role that Norman Shumway has played in the conduct of successful heart transplantation was to keep the sputtering flame alive, could be given to those who have unceasingly disseminate the intricate yet becomes eventually successful variant of in vitro endothelialization whether using gynecology microscopes or tissue-culture microscopes, to verify clinically the benefits of a principle and thus offer enough incentive for the efforts of today’s collaboration of experts leading towards a generally satisfactory breakthrough in various fields such as in microscopy, medicine and biology.